AdSpray, developed by Terumo, is a spray-type adhesion barrier that rapidly forms a biocompatible hydrogel—made from NHS-modified carboxymethyl dextrin—via mixing of dual solutions at the nozzle tip. Its delivery system allows insertion through a standard 5 mm trocar, enabling precise application even in irregular or complex surgical sites such as the pelvis. The misted spray quickly gels into a visible white barrier without needing dyes, facilitating real-time verification during surgery. Clinical evaluations have shown that AdSpray operates more quickly and easily than traditional sheet barriers, promoting safer, more efficient laparoscopic procedures.
Terumo AdSpray
Bio-absorbable adhesion barrier, designed to reduce postoperative adhesions by forming a fast-setting hydrogel directly on injured tissue surfaces. Delivered through a nozzle compatible with a 5 mm trocar, it ensures precise coverage and remains visible during application thanks to microbubble-generated opacity.
